Planta Medica, Table of Contents Planta Med 1999; 65(8): 712-714DOI: 10.1055/s-1999-14048 Original Paper Georg Thieme Verlag Stuttgart · New YorkIsoferulic Acid as Active Principle from the Rhizoma of Cimicifuga dahurica to Lower Plasma Glucose in Diabetic RatsI-Min Liu1 , Tzong-Cherng Chi1 , Feng-Lin Hsu2 , Chieh-Fu Chen3 , Juei-Tang Cheng1 1 Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan City, Taiwan, R.O.C. 2 Department of Medicinal Chemistry, School of Pharmacy, Taipei Medical College, Taipei City, Taiwan, R.O.C. 3 National Research Institute of Chinese Medicine, Taipei City, Taiwan, R.O.C. Recommend Article Abstract PDF Download(opens in new window) Buy Article(opens in new window) Abstract Isoferulic acid extracted from the rhizome of Cimicifuga dahurica Maxim. (Ranunculaceae) has been determined to have in vivo antihyperglycemic activity. An antihyperglycemic action of isoferulic acid in spontaneously diabetic rats, similar to type I diabetes, is presented. Key words Isoferulic acid - Cimicifuga dahurica - Ranunculaceae - glucose challenge - plasma glucose - hyperglycemia - diabetic rats PDF (171 kb)
